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SCHEMBL1064815

SCHEMBL1064815

O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)NCCN2C(=O)C=CC2=O)CCN(CC(=O)O)CC1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ PTGS1 P23219 4/20 0.41
▸ PTGS2 P35354 4/20 0.41
▸ DRD2 P14416 1/20 0.40
▸ DRD3 P35462 1/20 0.40
▸ TSHR P16473 1/20 0.39
▸ KMT2A Q03164 2/20 0.38
▸ LMNA P02545 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ GFER P55789 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15362875 1.00 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2PTGS1PTGS2DRD2
SCHEMBL15300102 0.92 DRD2 (0.40) ALDH1A1SMN1; SMN2PTGS1PTGS2DRD2
SCHEMBL25039413 0.91 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2PTGS1PTGS2DRD2
SCHEMBL12932661 0.88 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2PTGS1PTGS2DRD2
SCHEMBL9612244 0.84 KMT2A (0.47) ALDH1A1SMN1; SMN2TSHRKMT2AGAA
SCHEMBL22769435 0.83 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2TSHRKMT2ALMNA
SCHEMBL22344789 0.83 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2TSHRKMT2ALMNA
SCHEMBL27314981 0.83 PTGS1 (0.41) ALDH1A1SMN1; SMN2PTGS1PTGS2LMNA
SCHEMBL23014569 0.82 ALB (0.52) ALDH1A1SMN1; SMN2PTGS1PTGS2DRD2
SCHEMBL24728937 0.82 ALB (0.52) ALDH1A1SMN1; SMN2PTGS1PTGS2DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746921-A1 DRUG CONJUGATES OF IMIDAZOQUINOLINE AMINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF Canwell Biotech Limited (CN) 2026-05-27 — — EP claimed
US-12514937-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2026-01-06 — — US claimed
WO-2025016415-A1 DRUG CONJUGATES OF IMIDAZOQUINOLINE AMINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF CANWELL BIOTECH LIMITED (CN) 2025-01-23 — — WO claimed
WO-2025015586-A1 DRUG CONJUGATES OF IMIDAZOQUINOLINE AMINE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF CANWELL BIOTECH LIMITED (CN) 2025-01-23 — — WO claimed
CN-118814176-A Cleaning composition for chip after chemical mechanical polishing, preparation method and application thereof 浙江奥首材料科技有限公司 2024-10-22 — — CN claimed
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2024-09-12 — — US claimed
US-12016935-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2024-06-25 — — US claimed
CN-115177751-A Conjugates, methods of making and uses thereof 北京药明博锐生物科技有限公司 2022-10-14 — — CN claimed
US-20220001039-A1 COMPOSITIONS AND METHODS FOR DETECTING ACE2 EXPRESSION PROFILES WASHINGTON UNIVERSITY (US) 2022-01-06 — — US claimed
US-20200405889-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2020-12-31 — — US claimed
US-10329331-B2 Polypeptides AFFIBODY AB (SE) 2019-06-25 — — US claimed
US-20170348442-A1 COMPOSITIONS AND METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2017-12-07 — — US claimed
US-20160108095-A1 POLYPEPTIDES AFFIBODY AB (SE) 2016-04-21 — — US claimed
US-9211344-B2 Polypeptides AFFIBODY AB (SE) 2015-12-15 — — US claimed
US-8883120-B2 Polypeptides having affinity for HER2 AFFIBODY AB (SE) 2014-11-11 — — US claimed
US-20140162956-A1 POLYPEPTIDES AFFIBODY AB (SE) 2014-06-12 — — US claimed
US-20130280164-A1 POLYPEPTIDES HAVING AFFINITY FOR HER2 AFFIBODY AB (SE) 2013-10-24 — — US claimed
US-8501909-B2 Polypeptides having affinity for HER2 AFFIBODY AB (SE) 2013-08-06 — — US claimed
US-20110020223-A1 POLYPEPTIDES HAVING AFFINITY FOR HER2 AFFIBODY AB (SE) 2011-01-27 — — US claimed
EP-2072525-A1 New polypeptides having affinity for HER2 Affibody AB (SE) 2009-06-24 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020223-A1 POLYPEPTIDES HAVING AFFINITY FOR HER2 IGF2BP1, IGF2BP2, ERBB2 ALDH1A1 4801/4885SMN1; SMN2 2864/4885PTGS1 4100/4885
US-20170348442-A1 COMPOSITIONS AND METHODS FOR DETECTING CCR2 RECEPTORS CCR2, CCR1, CCR3 ALDH1A1 3034/4885SMN1; SMN2 2014/4885PTGS1 1506/4885
US-20200405889-A1 METHODS FOR DETECTING CCR2 RECEPTORS CCR2, CCR1, CCR5 ALDH1A1 2580/4885SMN1; SMN2 1780/4885PTGS1 1576/4885
US-12016935-B2 Methods for detecting CCR2 receptors CCR2, CCR1, CCR5 ALDH1A1 2580/4885SMN1; SMN2 1780/4885PTGS1 1576/4885
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS CCR2, CCR1, CCR5 ALDH1A1 2580/4885SMN1; SMN2 1780/4885PTGS1 1576/4885
US-20130280164-A1 POLYPEPTIDES HAVING AFFINITY FOR HER2 IGF2BP1, IGF2BP2, ERBB2 ALDH1A1 4801/4885SMN1; SMN2 2864/4885PTGS1 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.