Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586498 | 0.96 | KMT2A (0.44) | KMT2AGAASMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL9972165 | 0.95 | KMT2A (0.43) | KMT2AGAASMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL16526510 | 0.93 | KMT2A (0.42) | KMT2AGAASMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL17029296 | 0.93 | KMT2A (0.42) | KMT2AGAASMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL16356426 | 0.92 | GAA (0.46) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15290261 | 0.86 | HDAC1 (0.48) | KMT2AALDH1A1ACHECYP2D6 | |
| SCHEMBL9612258 | 0.84 | AKT1 (0.43) | KMT2AGAASMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL1064815 | 0.84 | ALDH1A1 (0.44) | KMT2AGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL15362875 | 0.84 | ALDH1A1 (0.44) | KMT2AGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22421442 | 0.83 | KMT2A (0.43) | KMT2AGAASMN1; SMN2ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220031870-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | UNIVERSITY OF SOUTHAMPTON (GB) | 2022-02-03 | — | — | US | disclosed |
| US-11135322-B2 | Radiofluorination method | GE HEALTHCARE LIMITED (GB) | 2021-10-05 | — | — | US | disclosed |
| EP-2651411-B1 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | IMMUNOMEDICS, INC. | 2016-07-14 | — | — | US | disclosed |
| US-20160082136-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | UNIVERSITY OF SOUTHAMPTON (GB) | 2016-03-24 | — | — | US | disclosed |
| US-20150307524-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2015-10-29 | — | — | US | disclosed |
| US-9115172-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-9028800-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20150057432-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8545809-B2 | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20130211044-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8496912-B2 | In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents | IMMUNOMEDICS, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-20130171065-A1 | In Vivo Copper-Free Click Chemistry for Delivery of Therapeutic and/or Diagnostic Agents | IMMUNOMEDICS, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8398956-B2 | In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents | IMMUNOMEDICS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120282178-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-11-08 | — | — | US | disclosed |
| US-8202509-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
| US-20110110854-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11135322-B2 | Radiofluorination method | TFRC, AFF1, AFF2 | KMT2A 2464/4885GAA 813/4885SMN1; SMN2 4161/4885 |
| US-20150057432-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | KMT2A 2972/4885GAA 620/4885SMN1; SMN2 1370/4885 |
| US-20110110854-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, F13A1, FCGRT | KMT2A 2153/4885GAA 302/4885SMN1; SMN2 2037/4885 |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | BRS3, BRCA1, MRE11 | KMT2A 3986/4885GAA 3845/4885SMN1; SMN2 2051/4885 |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | KMT2A 2486/4885GAA 654/4885SMN1; SMN2 1351/4885 |
| US-20120282178-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, F13A1, FCGRT | KMT2A 2153/4885GAA 302/4885SMN1; SMN2 2037/4885 |
| US-20130211044-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, F13A1, FCGRT | KMT2A 2153/4885GAA 302/4885SMN1; SMN2 2037/4885 |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | KMT2A 2486/4885GAA 654/4885SMN1; SMN2 1351/4885 |
| US-20150307524-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | KMT2A 2972/4885GAA 620/4885SMN1; SMN2 1370/4885 |
| US-20220031870-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | FOS, FGB, FOSB | KMT2A 1672/4885GAA 2027/4885SMN1; SMN2 1614/4885 |
| US-20130171065-A1 | In Vivo Copper-Free Click Chemistry for Delivery of Therapeutic and/or Diagnostic Agents | TIE1, C9, NCLN | KMT2A 3209/4885GAA 1657/4885SMN1; SMN2 1158/4885 |
| US-20160082136-A1 | METAL COMPLEXES AND FLUORINATION THEREOF | FOS, FGB, FOSB | KMT2A 1784/4885GAA 2075/4885SMN1; SMN2 1557/4885 |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | KMT2A 2972/4885GAA 620/4885SMN1; SMN2 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.