SCHEMBL9973863

SCHEMBL9973863

Cc1ccc(O)cc1NC(=O)CCc1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.49
SELP P16109 1/20 0.49
SELE P16581 1/20 0.49
LMNA P02545 2/20 0.48
ALDH1A1 P00352 3/20 0.47
RAB9A P51151 2/20 0.47
HCAR2 Q8TDS4 3/20 0.46
GAA P10253 2/20 0.45
POLB P06746 1/20 0.45
KMT2A Q03164 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9973860 0.89 SELL (0.51) SELLSELPSELEGAAPOLB
SCHEMBL9973859 0.86 HDAC3 (0.57) LMNAALDH1A1RAB9APOLBKMT2A
SCHEMBL9973864 0.84 HDAC3 (0.52) RAB9AHCAR2POLBHDAC3HDAC4
SCHEMBL14227348 0.83 LMNA (0.67) SELLSELPSELELMNAALDH1A1
SCHEMBL6103747 0.83 HCAR2 (0.57) HCAR2KMT2A
SCHEMBL6102325 0.81 MEN1 (0.58) ALDH1A1HCAR2KMT2AHSD17B10KDM4E
SCHEMBL14227347 0.81 MEN1 (0.59) LMNAALDH1A1RAB9AGAAPOLB
SCHEMBL14227343 0.80 ALDH1A1 (0.57) SELLSELPSELELMNAALDH1A1
SCHEMBL9973870 0.80 LMNA (0.55) SELLSELPSELELMNAALDH1A1
SCHEMBL14227344 0.80 SELP (0.60) SELLSELPSELELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8409552-B2 Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds SYMRISE AG (DE) 2013-04-02 US disclosed
US-8203016-B2 Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents SYMRISE AG (DE) 2012-06-19 US disclosed
US-20090297468-A1 Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching SYMRISE GMBH & CO. KG (DE) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090297468-A1 Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching H1-0, ASIC1, MCOLN1 SELL 4804/4885SELP 4878/4885SELE 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.