Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ARG1 | P05089 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 2/20 | 0.44 |
| ▸ | KDM6A | O15550 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929328 | 1.00 | APP (0.49) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL13349956 | 0.85 | ARG1 (0.42) | APPHRH3KDM4EARG1DOHH | |
| SCHEMBL9513592 | 0.82 | APP (0.61) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL10359200 | 0.82 | APP (0.61) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL18379366 | 0.82 | APP (0.50) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL113644 | 0.79 | KDM4E (0.47) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL113697 | 0.79 | KDM4E (0.47) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL16625508 | 0.79 | KDM4E (0.52) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL16625510 | 0.79 | KDM4E (0.52) | APPHRH3KDM4ETP53CYP2D6 | |
| SCHEMBL9700234 | 0.79 | KDM4E (0.55) | APPHRH3KDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370177-B1 | NOVEL COSMETIC COMPOSITIONS HAVING HAIR GROWTH INHIBITING EFFECT | HENKEL AG & CO KGAA (DE) | 2017-11-15 | — | — | EP | disclosed |
| EP-2370050-B1 | NOVEL DEODORANTS AND ANTIPERSPIRANTS HAVING HAIR GROWTH INHIBITING EFFECT | HENKEL AG & CO KGAA (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-8202892-B2 | Advanced glycation end products as active ingredients | HENKEL AG & CO. KGAA (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8202892-B2 | Advanced glycation end products as active ingredients | HENKEL AG & CO. KGAA (DE) | 2012-06-19 | — | — | US | disclosed |
| WO-2011131474-A2 | SKIN-GENTLE DEODORANTS AND ANTIPERSPIRANTS | HENKEL AG & CO. KGAA (DE) | 2011-10-27 | — | — | WO | disclosed |
| WO-2010102863-A1 | BIOLOGICALLY DEGRADABLE BUILDER SUBSTANCES AND CO-TENSIDES | HENKEL AG & CO. KGAA (DE) | 2010-09-16 | — | — | WO | disclosed |
| US-20100204176-A1 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
| US-20100204176-A1 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
| WO-2010063678-A2 | NOVEL DEODORANTS AND ANTIPERSPIRANTS HAVING HAIR GROWTH INHIBITING EFFECT | HENKEL AG & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010063673-A2 | NOVEL COSMETIC COMPOSITIONS HAVING HAIR GROWTH INHIBITING EFFECT | HENKEL AG & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009007257-A2 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | HENKEL AG & CO. KGAA (DE) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204176-A1 | ADVANCED GLYCATION END PRODUCTS AS ACTIVE INGREDIENTS | AGER, GLA, TYR | APP 192/4885HRH3 507/4885KDM4E 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.