Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GRN | P28799 | 1/20 | 0.31 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441151 | 0.90 | PKM (0.33) | PKMKMT2AKDM4EGRNSORT1 | |
| SCHEMBL12887762 | 0.89 | PKM (0.40) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL2611106 | 0.85 | PKM (0.45) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL10221896 | 0.82 | KDM4E (0.47) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL16642354 | 0.78 | BAZ2B (0.35) | ALDH1A1KDM4EGRNSORT1 | |
| SCHEMBL8932305 | 0.76 | KDM4E (0.34) | NPC1ALDH1A1RAB9AKDM4EGRN | |
| SCHEMBL17493311 | 0.76 | KMT2A (0.34) | KMT2AKDM4EGRNSORT1 | |
| SCHEMBL9607540 | 0.73 | KDM4E (0.39) | PKMNPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL3436871 | 0.72 | PKM (0.45) | PKMNPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL2611143 | 0.72 | PKM (0.45) | PKMNPC1ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | BAYER CROPSCIENCE AG (DE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | DDT, NPEPPS, PTMS | PKM 467/4885NPC1 4842/4885ALDH1A1 2780/4885 |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | NPEPPS, DDT, DNPEP | PKM 508/4885NPC1 4786/4885ALDH1A1 3415/4885 |
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | DDT, NQO2, NIT2 | PKM 2479/4885NPC1 3027/4885ALDH1A1 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.