Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537472 | 0.83 | HDAC3 (0.41) | KDM4EGRNSORT1HDAC3HDAC4 | |
| SCHEMBL25908750 | 0.80 | KDM4E (0.34) | KDM4EGRNSORT1HDAC3HDAC4 | |
| SCHEMBL16946322 | 0.80 | KDM4E (0.34) | KDM4EGRNSORT1HDAC3HDAC4 | |
| SCHEMBL3441151 | 0.78 | PKM (0.33) | KDM4EGRNSORT1 | |
| SCHEMBL16642354 | 0.78 | BAZ2B (0.35) | KDM4EGRNSORT1ALDH1A1 | |
| SCHEMBL8932286 | 0.77 | KDM4E (0.55) | KDM4EGRNSORT1 | |
| SCHEMBL9974256 | 0.76 | PKM (0.41) | KDM4EGRNSORT1HDAC3HDAC4 | |
| SCHEMBL17493311 | 0.76 | KMT2A (0.34) | KDM4EGRNSORT1 | |
| SCHEMBL28502037 | 0.75 | KDM4E (0.40) | KDM4EGRNSORT1 | |
| SCHEMBL2355530 | 0.74 | GRN (0.67) | KDM4EGRNSORT1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3665167-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-11-30 | — | — | EP | disclosed |
| US-11252963-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-22 | — | — | US | disclosed |
| US-11252963-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-02-22 | — | — | US | disclosed |
| US-11142519-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-12 | — | — | US | disclosed |
| US-11142519-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-12 | — | — | US | disclosed |
| CN-108713016-B | Pesticidally active pyrazole derivatives | 先正达参股股份有限公司 | 2021-10-08 | — | — | CN | disclosed |
| EP-3416959-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-12 | — | — | EP | disclosed |
| EP-3416959-B1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-12 | — | — | EP | disclosed |
| US-20210009573-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
| US-20210009573-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
| US-20200288713-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-17 | — | — | US | disclosed |
| US-20200288713-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-17 | — | — | US | disclosed |
| US-20200196603-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-25 | — | — | US | disclosed |
| US-20200196603-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-25 | — | — | US | disclosed |
| US-20190150441-A1 | PESTICIDALLY ACTIVE PRYAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-23 | — | — | US | disclosed |
| US-20190150441-A1 | PESTICIDALLY ACTIVE PRYAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-23 | — | — | US | disclosed |
| WO-2019030355-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
| WO-2019030358-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-14 | — | — | WO | disclosed |
| WO-2017140771-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-24 | — | — | WO | disclosed |
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11252963-B2 | Pesticidally active pyrazole derivatives | ACHE, AADAC, CAT | KDM4E 2972/4885GRN 2825/4885SORT1 4873/4885 |
| US-20200196603-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, CAT | KDM4E 2972/4885GRN 2825/4885SORT1 4873/4885 |
| US-20190150441-A1 | PESTICIDALLY ACTIVE PRYAZOLE DERIVATIVES | ACHE, PRXL2A, CASP7 | KDM4E 2291/4885GRN 3348/4885SORT1 4725/4885 |
| US-20210009573-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, CAT | KDM4E 2972/4885GRN 2825/4885SORT1 4873/4885 |
| US-20200288713-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, CAT | KDM4E 2972/4885GRN 2825/4885SORT1 4873/4885 |
| US-11142519-B2 | Pesticidally active pyrazole derivatives | ACHE, AADAC, CAT | KDM4E 2972/4885GRN 2825/4885SORT1 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.