Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938525 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL9974756 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL1093120 | 0.84 | ALDH1A1 (0.97) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL1981534 | 0.83 | ALDH1A1 (0.74) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL4676953 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL4679344 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL4675601 | 0.80 | ALDH1A1 (0.74) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL9684591 | 0.80 | ALDH1A1 (0.74) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 | |
| SCHEMBL4673014 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPK1HTTLMNAMAPT | |
| SCHEMBL6948430 | 0.77 | MAPK1 (0.68) | ALDH1A1MAPK1HTTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509951-B1 | NOVEL CATIONIC AMINOPYRIDINES, DYE COMPOSITION COMPRISING A CATIONIC AMINOPYRIDINE, PROCESSES THEREFOR AND USES THEREOF | ORÉAL L (FR) | 2016-04-13 | — | — | EP | disclosed |
| US-9220671-B2 | Dye composition comprising at least four dye precursors including at least one oxidation base and at least one coupler | L'OREAL (FR) | 2015-12-29 | — | — | US | disclosed |
| US-8491669-B2 | Cationic 4-aminopyridine, dye composition comprising a cationic 4-aminopyridine, processes therefor and uses thereof | L'OREAL (FR) | 2013-07-23 | — | — | US | disclosed |
| US-20130048007-A1 | NOVEL CATIONIC 4- AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2013-02-28 | — | — | US | disclosed |
| WO-2012080286-A9 | DYEING COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A CATIONIC 3,5-DIAMINOPYRIDINE COUPLER | L'OREAL (FR) | 2013-01-31 | — | — | WO | disclosed |
| WO-2012080289-A2 | DYE COMPOSITION COMPRISING AT LEAST FOUR DYE PRECURSORS INCLUDING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011069898-A1 | NOVEL CATIONIC AMINOPYRIDINES, DYE COMPOSITION COMPRISING A CATIONIC AMINOPYRIDINE, PROCESSES THEREFOR AND USES THEREOF | L'OREAL (FR) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130048007-A1 | NOVEL CATIONIC 4- AMINOINDOLES, DYE COMPOSITION COMPRISING A CATIONIC 4-AMINOINDOLE, PROCESSES THEREFOR AND USES THEREOF | TPH1, ALDH7A1, FARS2 | ALDH1A1 166/4885MAPK1 2143/4885HTT 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.