Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778693 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAEPHX2CA1CA2 | |
| SCHEMBL6686034 | 0.78 | L3MBTL1 (0.45) | SMN1; SMN2LMNAEPHX2CA1CA2 | |
| SCHEMBL630318 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAEPHX2CA1CA2 | |
| SCHEMBL8968921 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2LMNAEPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL1073954 | 0.74 | LMNA (0.48) | SMN1; SMN2LMNAEPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL15022007 | 0.74 | EPHX2 (0.49) | SMN1; SMN2LMNAEPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL12344538 | 0.74 | LMNA (0.48) | SMN1; SMN2LMNAEPHX2CA1CA2 | |
| SCHEMBL5385637 | 0.74 | LMNA (0.48) | SMN1; SMN2LMNAEPHX2CA1CA2 | |
| SCHEMBL14573044 | 0.74 | EPHX2 (0.53) | SMN1; SMN2LMNAEPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL24927361 | 0.72 | EPHX1 (0.43) | SMN1; SMN2LMNAEPHX2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202910-B2 | Compositions and methods for treatment of infectious disease | SEQUELLA, INC. (US) | 2012-06-19 | — | — | US | disclosed |