Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974962 | 0.92 | NPC1 (0.49) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL9974931 | 0.88 | KDM4E (0.52) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL9974996 | 0.86 | KDM4E (0.50) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL9974965 | 0.84 | NPC1 (0.48) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL14655918 | 0.84 | KDM4E (0.56) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL29725567 | 0.83 | KDM4E (0.68) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL13910993 | 0.83 | KDM4E (0.68) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL9974943 | 0.83 | KDM4E (0.46) | RAB9ANPC1KDM4ELMNACCR1 | |
| SCHEMBL9974995 | 0.82 | RAB9A (0.52) | RAB9ANPC1KDM4ELMNATP53 | |
| SCHEMBL9974907 | 0.80 | LMNA (0.52) | RAB9ANPC1KDM4ELMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081541-A1 | 1, 2, 4, 5-SUBSTITUTED PHENYL DERIVATIVE, PRODUCTION METHOD FOR SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |