Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 11/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151498 | 1.00 | PSMB1 (0.41) | PSMB1PSMB5PSMB2LMNAHRH3 | |
| Hydrochloric Acid SCHEMBL28035282 | 0.98 | PSMB1 (0.41) | PSMB1PSMB5PSMB2LMNAHRH3 | |
| SCHEMBL6978681 | 0.98 | PSMB1 (0.39) | PSMB1PSMB5PSMB2LMNANPC1 | |
| SCHEMBL14667509 | 0.89 | HRH3 (0.45) | HRH3KDM4EPOLBMAPT | |
| SCHEMBL6976253 | 0.84 | PAOX (0.39) | HRH3NPC1KDM4EALDH1A1 | |
| SCHEMBL9945570 | 0.83 | PSMB1 (0.40) | PSMB1PSMB5PSMB2LMNANPC1 | |
| SCHEMBL9944262 | 0.83 | PSMB1 (0.43) | PSMB1PSMB5PSMB2LMNAHRH3 | |
| SCHEMBL6957764 | 0.82 | PSMB1 (0.40) | PSMB1PSMB5PSMB2LMNAHRH3 | |
| SCHEMBL6977002 | 0.81 | ALDH1A1 (0.42) | HRH3KDM4EALDH1A1POLB | |
| SCHEMBL6976865 | 0.81 | PSMB1 (0.36) | PSMB1PSMB5PSMB2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819360-B | A kind of amine alcoxyl amido replaces curcumin chemical compounds and its preparation method and application | HUZHOU TEACHERS COLLEGE (CN) | 2015-10-28 | — | — | CN | disclosed |
| US-8772290-B2 | Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same | Oscotech Inc. (KR) | 2014-07-08 | — | — | US | disclosed |
| US-8202879-B2 | Quinazoline derivatives having tyrosine kinase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2012-06-19 | — | — | US | disclosed |
| US-20100249082-A1 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES | Bionaut Pharmaceuticals INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-20090143414-A1 | Quinazoline Derivatives Having Tyrosine Kinase Inhibitory Activity | SHIONOGI & CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143414-A1 | Quinazoline Derivatives Having Tyrosine Kinase Inhibitory Activity | ERBB2, EGFR, ABL1 | PSMB1 2822/4885PSMB5 2481/4885PSMB2 2104/4885 |
| US-20100249082-A1 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES | HIF1AN, HIF1A, HYOU1 | PSMB1 3307/4885PSMB5 3910/4885PSMB2 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.