SCHEMBL9975429

SCHEMBL9975429

CC(O)P(=O)(C/C=C/C=C/c1ccccc1)C(C)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.44
CYP3A4 P08684 1/20 0.43
HTR2A P28223 3/20 0.40
GLA P06280 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
HDAC5 Q9UQL6 2/20 0.39
TRPA1 O75762 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
ALOX5 P09917 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9975422 0.89 HTR2A (0.47) MAOBHTR2AGLATDP1HDAC3
SCHEMBL9973883 0.78 MAOB (0.52) MAOBCYP3A4HTR2AGLATDP1
SCHEMBL27696701 0.73 MAOB (0.67) MAOBCYP3A4HTR2AGLATDP1
SCHEMBL13142763 0.72 NR1I2 (0.46) MAOBCYP3A4GLATDP1HDAC3
SCHEMBL27923443 0.71 MAOB (0.47) MAOBCYP3A4HTR2AGLATDP1
SCHEMBL12467618 0.71 THRB (0.49) CYP3A4TDP1HDAC3HDAC1HDAC2
SCHEMBL7145801 0.71 MAOB (0.56) MAOBCYP3A4HTR2AGLATDP1
SCHEMBL10950999 0.69 MAOB (0.58) MAOBCYP3A4HTR2AGLATDP1
SCHEMBL7550554 0.69 MAOB (0.58) MAOBCYP3A4HTR2AGLATDP1
SCHEMBL7958229 0.69 MAOB (0.58) MAOBCYP3A4HTR2AGLATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156600-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS USING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed
US-7803507-B2 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2010-09-28 US disclosed
US-7615326-B2 Electrophotographic photoconductor and image forming apparatus SHARP KABUSHIKI KAISHA (JP) 2009-11-10 US disclosed
US-7416824-B2 Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same SHARP KABUSHIKI KAISHA (JP) 2008-08-26 US disclosed