SCHEMBL9975422

SCHEMBL9975422

CC(O)P(=O)(C/C=C/c1ccccc1)C(C)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.47
PAM P19021 1/20 0.46
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
PTGER4 P35408 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9975429 0.89 MAOB (0.44) HTR2APAMTSHRHDAC3TNKS
SCHEMBL12467618 0.81 THRB (0.49) TSHRHDAC3HDAC1HDAC2HDAC8
SCHEMBL5611194 0.76 PAM (0.53) HTR2APAMHDAC3TNKSHDAC4
SCHEMBL5611191 0.76 PAM (0.53) HTR2APAMHDAC3TNKSHDAC4
SCHEMBL9973879 0.76 PAM (0.48) HTR2APAMMEN1KMT2AMAOB
SCHEMBL28995211 0.74 PAM (0.52) HTR2APAMHDAC3TNKSHDAC4
SCHEMBL28995212 0.74 PAM (0.52) HTR2APAMHDAC3TNKSHDAC4
SCHEMBL27831824 0.73 PAM (0.50) HTR2APAMHDAC3TNKSHDAC4
SCHEMBL5475692 0.72 HTR2A (0.66) HTR2APAMTSHRMAOBGRIK1
SCHEMBL5475689 0.72 HTR2A (0.66) HTR2APAMTSHRMAOBGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156600-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS USING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed
US-8003287-B2 Low temperature charge transportability and potential, sensitivity and photoresponsiveness; durability SHARP KABUSHIKI KAISHA (JP) 2011-08-23 US disclosed
US-20110104600-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS USING THE SAME SHARP KABUSHIKI KAISHA (JP) 2011-05-05 US disclosed
US-7803507-B2 Electrophotographic photoreceptor and image forming apparatus including the same SHARP KABUSHIKI KAISHA (JP) 2010-09-28 US disclosed
US-7416824-B2 Organic photoconductive material electrophotographic photoreceptor and image forming apparatus using the same SHARP KABUSHIKI KAISHA (JP) 2008-08-26 US disclosed
US-20080166642-A1 Electrophotographic photoconductor and image-forming apparatus SHARP KABUSHIKI KAISHA (JP) 2008-07-10 US disclosed