Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430386 | 1.00 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTGRIN2DGRIN3B | |
| SCHEMBL29796685 | 0.85 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTGRIN2DGRIN3B | |
| SCHEMBL43993 | 0.85 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTGRIN2DGRIN3B | |
| SCHEMBL11315933 | 0.81 | TSHR (0.35) | ALDH1A1POLBMAPT | |
| SCHEMBL11221409 | 0.81 | ALDH1A1 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL30038608 | 0.81 | ALDH1A1 (0.32) | ALDH1A1POLBMAPT | |
| SCHEMBL2945876 | 0.80 | ALDH1A1 (0.31) | ALDH1A1POLBMAPT | |
| SCHEMBL9718333 | 0.78 | LMNA (0.39) | ALDH1A1POLBMAPT | |
| SCHEMBL11570327 | 0.76 | TSHR (0.40) | ALDH1A1 | |
| SCHEMBL4445941 | 0.76 | LMNA (0.36) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139736-B2 | Surface-modified silicic acid semi-gels | EVONIK DEGUSSA GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-20120156470-A1 | SURFACE-MODIFIED SILICIC ACID SEMI-GELS | EVONIK DEGUSSA GMBH (DE) | 2012-06-21 | — | — | US | disclosed |
| US-8038787-B2 | Coating formulation having improved rheological properties | EVONIK DEGUSSA GMBH (DE) | 2011-10-18 | — | — | US | disclosed |
| EP-1607421-B1 | Painting composition having improved rheological characteristics | DEGUSSA (DE) | 2007-08-29 | — | — | EP | disclosed |