Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.54 |
| ▸ | GPX4 | P36969 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997137 | 0.86 | TRPV1 (0.61) | TRPV1GPX4 | |
| SCHEMBL6006640 | 0.81 | GPX4 (0.55) | TRPV1GPX4KMT2AFAAH | |
| SCHEMBL1000937 | 0.80 | TRPV1 (0.72) | TRPV1KMT2A | |
| SCHEMBL1000384 | 0.80 | KMT2A (0.77) | TRPV1GPX4KMT2A | |
| SCHEMBL999152 | 0.79 | KMT2A (0.72) | TRPV1GPX4KMT2A | |
| SCHEMBL998353 | 0.78 | KMT2A (0.71) | TRPV1GPX4KMT2A | |
| SCHEMBL1000958 | 0.78 | LMNA (0.71) | TRPV1GPX4CDK4CCND1FAAH | |
| SCHEMBL999029 | 0.78 | KMT2A (0.56) | TRPV1GPX4KMT2AFAAH | |
| SCHEMBL997783 | 0.77 | MAPT (0.60) | KMT2A | |
| SCHEMBL1000938 | 0.75 | MAPT (0.78) | TRPV1GPX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872133-B2 | Tricyclic heterocycle compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |