Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989305 | 0.88 | RAB9A (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL2983083 | 0.85 | SORT1 (0.53) | RAB9ANPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL9979763 | 0.84 | RAB9A (0.50) | RAB9ANPC1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL3160357 | 0.82 | POLB (0.67) | RAB9ANPC1ALDH1A1POLBKDM4E | |
| SCHEMBL6261356 | 0.80 | RAB9A (0.64) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2984797 | 0.78 | SORT1 (0.62) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19651332 | 0.77 | KDM4E (0.70) | RAB9ANPC1ALDH1A1POLBKDM4E | |
| SCHEMBL6595792 | 0.77 | F10 (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL6592032 | 0.76 | RAB9A (0.56) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8355348 | 0.76 | F10 (0.65) | RAB9ANPC1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | disclosed |