Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966581 | 0.91 | SIGMAR1 (0.56) | SIGMAR1TSHRALDH1A1KDM4ECDC25B | |
| SCHEMBL996368 | 0.84 | ALDH1A1 (0.45) | GAAALDH1A1CA12CA1CA2 | |
| SCHEMBL995336 | 0.81 | CA12 (0.46) | SIGMAR1GAATSHRALDH1A1CA12 | |
| SCHEMBL18249419 | 0.79 | KDM4E (0.48) | GAATSHRALDH1A1KDM4ECA12 | |
| SCHEMBL9224528 | 0.77 | TSHR (0.50) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL20164248 | 0.76 | PTGS2 (0.42) | TSHRALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL15016098 | 0.75 | HPGD (0.41) | GAATSHRALDH1A1KDM4ECDC25B | |
| SCHEMBL27466253 | 0.75 | TSHR (0.47) | TSHRALDH1A1CDC25BLMNACYP3A4 | |
| SCHEMBL798942 | 0.75 | NR4A2 (0.49) | ALDH1A1LMNANPSR1CYP3A4CYP1A2 | |
| SCHEMBL18249478 | 0.75 | TSHR (0.41) | TSHRALDH1A1KDM4ELMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809574-B2 | Method for preparing isocyanates by liquid-phase thermal cracking | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2014-08-19 | — | — | US | disclosed |
| US-20110021810-A1 | METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021810-A1 | METHOD FOR PREPARING ISOCYANATES BY LIQUID-PHASE THERMAL CRACKING | DBI, CCNI, DGKI | SIGMAR1 1697/4885GAA 4550/4885TSHR 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.