Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | YWHAG | P61981 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069007 | 0.84 | MAPT (0.51) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL10069008 | 0.83 | MAPT (0.55) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL9976615 | 0.80 | APP (0.54) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL4448682 | 0.78 | MAPT (0.62) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL19785179 | 0.77 | MAPT (0.69) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL28557038 | 0.77 | MAPT (0.65) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL31542971 | 0.76 | MAPT (0.56) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL18998959 | 0.75 | APP (0.73) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL20730239 | 0.74 | APP (0.77) | MAPTHSD17B10HPGDHIF1AKDM4E | |
| SCHEMBL21388223 | 0.73 | MAPT (0.59) | MAPTHSD17B10HPGDHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | NANOSCALE CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | PREP, HPN, ADAM9 | MAPT 905/4885HSD17B10 3050/4885HPGD 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.