ADAM9 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL995018	1.00	2/20
SCHEMBL995021	1.00	2/20
SCHEMBL995886	1.00	2/20
SCHEMBL995891	1.00	2/20
Apratastat (SCHEMBL2834310)	1.00	2/20
Apratastat (SCHEMBL3946334)	1.00	2/20
SCHEMBL995008	0.90	2/20
SCHEMBL995010	0.90	2/20
SCHEMBL3941060	0.90	2/20
SCHEMBL995212	0.89	2/20
SCHEMBL995213	0.89	2/20
SCHEMBL996195	0.89	2/20
SCHEMBL996197	0.89	2/20
SCHEMBL997163	0.88	2/20
SCHEMBL997164	0.88	2/20
SCHEMBL3944800	0.86	2/20
SCHEMBL3941871	0.86	2/20
SCHEMBL995733	0.86	2/20
SCHEMBL995738	0.86	2/20
SCHEMBL996486	0.85	2/20

Clinical trials — most relevant to ADAM9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy	PHASE4	NOT_YET_RECRUITING
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.	PHASE4	COMPLETED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
Tranexamic Acid (TXA) and Corona Virus 2019 (COVID19) in Inpatients	PHASE2	WITHDRAWN
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Exercise and the Receptor for Advanced Glycation End Products (RAGE)	nan	COMPLETED
Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1	nan	UNKNOWN
Extracellular Matrix Remodeling of the Umbilical Cord and Placenta in Preeclampsia	nan	UNKNOWN
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
Peri-implantitis and MMP-8	nan	COMPLETED
Multicentre Trial Of Serum Levels Of MMP-9 As A Biomarker Of Endoleak	nan	COMPLETED
Salivary Markers in Periodontal Disorders	nan	COMPLETED
Abnormal 3-D MRI Flow Patterns in Adolescents Patients With Bicuspid Aortic Valve	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
MMP-9, TIMP-9 in Lung Imaging and Functional of COVID-19	nan	COMPLETED
Apoptosis Markers in Aggressive Periodontitis	nan	COMPLETED
Pharmacokinetics of Low Molecular Weight Heparin in Cancer Patients	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ADAM9 binder may also engage these)

Protein	Name	Similarity
Q61072	—	1.000	Q61072 →
Q4VC17	—	0.982	Q4VC17 →
Q8TE60	—	0.981	Q8TE60 →
ADAM12	Disintegrin and metalloproteinase domain-containing protein 12	0.977	landscape →
O35674	—	0.974	O35674 →
Q61824	—	0.974	Q61824 →
P59511	—	0.972	P59511 →
P97857	—	0.969	P97857 →
Q9H013	—	0.969	Q9H013 →
Q8TE57	—	0.968	Q8TE57 →
Q9P2N4	—	0.968	Q9P2N4 →
Q69Z28	—	0.968	Q69Z28 →
Q8TC27	—	0.966	Q8TC27 →
Q9R1V6	—	0.966	Q9R1V6 →
Q8TE58	—	0.966	Q8TE58 →
Q9WUQ1	—	0.966	Q9WUQ1 →
Q9XSL6	—	0.966	Q9XSL6 →
ADAMTS1	A disintegrin and metalloproteinase with thrombospondin motifs 1	0.966	landscape →
Q9UKJ8	—	0.966	Q9UKJ8 →
Q05910	—	0.965	Q05910 →
Q28483	—	0.965	Q28483 →
Q9P0K1	—	0.964	Q9P0K1 →
Q9VAC5	—	0.964	Q9VAC5 →
Q9Y3Q7	—	0.963	Q9Y3Q7 →
P57110	—	0.963	P57110 →
ITGB3	Integrin beta-3	0.963	landscape →
O70309	—	0.963	O70309 →
Q95194	—	0.963	Q95194 →
ENPP1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1	0.963	landscape →
MEP1A	Meprin A subunit alpha	0.962	landscape →