Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611603 | 0.78 | TSHR (0.42) | ALDH1A1TSHRPTPN1NR1H2NR1H3 | |
| SCHEMBL14101146 | 0.78 | TSHR (0.42) | ALDH1A1TSHRPTPN1ATMCYP2D6 | |
| SCHEMBL16428437 | 0.77 | TSHR (0.46) | ALDH1A1TSHRPTPN1NR1H2NR1H3 | |
| SCHEMBL17974909 | 0.75 | NR1H2 (0.44) | ALDH1A1TSHRPTPN1NR1H2NR1H3 | |
| SCHEMBL20945461 | 0.74 | NR1H2 (0.58) | NR1H2MAPT | |
| SCHEMBL28135290 | 0.73 | TSHR (0.46) | ALDH1A1TSHRPTPN1ATMCYP2D6 | |
| SCHEMBL5709190 | 0.73 | KCNN4 (0.46) | ALDH1A1TSHRPTPN1ATMCYP2D6 | |
| SCHEMBL8755619 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRATMCYP2D6DRD2 | |
| SCHEMBL639889 | 0.72 | ATM (0.41) | ALDH1A1TSHRPTPN1ATMCYP2D6 | |
| SCHEMBL6846624 | 0.72 | ATM (0.41) | ALDH1A1TSHRPTPN1ATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1225497-A | — | — | None | — | — | JP | disclosed |
| US-8614081-B2 | Nitrilase biocatalysts | CODEXIS, INC. (US) | 2013-12-24 | — | — | US | disclosed |
| US-20120142063-A1 | NITRILASE BIOCATALYSTS | Codexis ,Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142063-A1 | NITRILASE BIOCATALYSTS | Codexis ,Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142063-A1 | NITRILASE BIOCATALYSTS | Codexis ,Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| WO-2011011630-A2 | NITRILASE BIOCATALYSTS | CODEXIS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011011630-A2 | NITRILASE BIOCATALYSTS | CODEXIS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| CN-101426769-A | Five-membered heterocyclic invertebrate pest control agents | DU PONT (US) | 2009-05-06 | — | — | CN | disclosed |
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |
| EP-0681713-B1 | SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE | CLARIANT GMBH (DE) | 1998-11-18 | — | — | EP | disclosed |
| US-5716756-A | POSITIVE OR NEGATIVE WORKING MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| EP-0681713-A1 | SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994018606-A1 | SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE | HOESCHT AKTIENGESELLSCHAFT (DE) | 1994-08-18 | — | — | WO | disclosed |
| JP-H01225497-A | PRODUCTION OF CARBOXYLIC ACID ESTER OF OPTICALLY ACTIVE FLUORINE-CONTAINING CYANOHYDRIN | CENTRAL GLASS CO LTD | 1989-09-08 | — | — | JP | disclosed |