Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9977545 | 0.82 | PTGS1 (0.34) | HTR7NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL9977571 | 0.82 | PTGS1 (0.34) | HTR7NPC1RAB9APTGS1PTGS2 | |
| SCHEMBL9977568 | 0.81 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL9977551 | 0.81 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL9977594 | 0.79 | TBXAS1 (0.37) | HTR7NPC1RAB9AGAAPOLB | |
| SCHEMBL9977598 | 0.79 | TBXAS1 (0.37) | HTR7NPC1RAB9AGAAPOLB | |
| SCHEMBL9977572 | 0.78 | NPC1 (0.53) | HTR7PTPN1NPC1RAB9ALMNA | |
| SCHEMBL9977573 | 0.77 | MAPT (0.37) | HTR7LMNA | |
| SCHEMBL15417850 | 0.77 | MAPT (0.37) | HTR7LMNA | |
| SCHEMBL9977601 | 0.76 | CXCR1 (0.36) | GAAPOLBLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465847-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2012-06-20 | — | — | EP | disclosed |