Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9977545 | 1.00 | PTGS1 (0.34) | PTGS1PTGS2FNTAFNTBHTR7 | |
| SCHEMBL9977568 | 0.87 | PTGS1 (0.33) | PTGS1PTGS2FNTAFNTB | |
| SCHEMBL9977551 | 0.87 | PTGS1 (0.33) | PTGS1PTGS2FNTAFNTB | |
| SCHEMBL9977594 | 0.83 | TBXAS1 (0.37) | PTGS1PTGS2FNTAFNTBHTR7 | |
| SCHEMBL9977598 | 0.83 | TBXAS1 (0.37) | PTGS1PTGS2FNTAFNTBHTR7 | |
| SCHEMBL9977570 | 0.82 | HTR7 (0.33) | PTGS1PTGS2HTR7NPC1RAB9A | |
| SCHEMBL9977601 | 0.80 | CXCR1 (0.36) | FNTAFNTB | |
| SCHEMBL9977596 | 0.80 | CXCR1 (0.36) | FNTAFNTB | |
| SCHEMBL9977595 | 0.78 | ADRB2 (0.36) | — | |
| SCHEMBL9977567 | 0.78 | ADRB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465847-B1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2016-10-12 | — | — | EP | disclosed |
| US-8623855-B2 | Azetidinone compounds and medical use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2014-01-07 | — | — | US | disclosed |
| EP-2465847-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2012-06-20 | — | — | EP | disclosed |