Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 5/20 | 0.32 |
| ▸ | NOS1 | P29475 | 5/20 | 0.32 |
| ▸ | NOS2 | P35228 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9977595 | 0.88 | ADRB2 (0.36) | ADRB2ADRB1ADRB3LMNANOS3 | |
| SCHEMBL9977567 | 0.88 | ADRB2 (0.36) | ADRB2ADRB1ADRB3LMNANOS3 | |
| SCHEMBL9977600 | 0.86 | ADRB2 (0.34) | ADRB2ADRB1ADRB3LMNANOS3 | |
| SCHEMBL9977609 | 0.86 | ADRB2 (0.34) | ADRB2ADRB1ADRB3LMNANOS3 | |
| SCHEMBL9977601 | 0.79 | CXCR1 (0.36) | ADRB2ADRB1ADRB3LMNASMN1; SMN2 | |
| SCHEMBL9977596 | 0.79 | CXCR1 (0.36) | ADRB2ADRB1ADRB3LMNASMN1; SMN2 | |
| SCHEMBL9977573 | 0.76 | MAPT (0.37) | LMNASMN1; SMN2 | |
| SCHEMBL15417850 | 0.76 | MAPT (0.37) | LMNASMN1; SMN2 | |
| SCHEMBL9977545 | 0.76 | PTGS1 (0.34) | — | |
| SCHEMBL9977571 | 0.76 | PTGS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465847-A1 | AZETIDINONE COMPOUNDS AND MEDICAL USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2012-06-20 | — | — | EP | disclosed |