Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13012717 | 0.70 | ATM (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9970859 | 0.70 | ALDH1A1 (0.38) | MEN1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL9977802 | 0.70 | HPGD (0.31) | HPGDTSHRALDH1A1 | |
| SCHEMBL9977800 | 0.65 | TSHR (0.33) | HPGDTSHRALDH1A1 | |
| SCHEMBL19567960 | 0.61 | PRKCA (0.36) | HPGDTSHRALDH1A1 | |
| SCHEMBL23199851 | 0.61 | ALDH1A1 (0.47) | MEN1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL16391280 | 0.60 | ALDH1A1 (0.45) | MEN1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL6275471 | 0.60 | — | — | |
| SCHEMBL14968290 | 0.59 | ALDH1A1 (0.40) | MEN1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL21122614 | 0.59 | TSHR (0.45) | MEN1KMT2AHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083117-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-21 | — | — | WO | disclosed |