SCHEMBL9978110

SCHEMBL9978110

C=CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.70
EGFR P00533 1/20 0.68
ALDH1A1 P00352 4/20 0.66
KMT2A Q03164 4/20 0.66
POLB P06746 2/20 0.66
MEN1 O00255 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
RXFP1 Q9HBX9 1/20 0.58
LMNA P02545 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
GPR27 Q9NS67 1/20 0.57
THRB P10828 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29277100 0.85 L3MBTL1 (0.68) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL13212196 0.83 KMT2A (0.67) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL547543 0.83 KDM4E (1.00) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL31497258 0.82 KDM4E (0.62) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL12464040 0.81 KDM4E (0.69) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL10031583 0.81 KDM4E (0.77) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL3820009 0.81 TGM2 (0.67) ALDH1A1KMT2APOLBMEN1SMN1; SMN2
SCHEMBL13212163 0.80 KMT2A (0.68) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL13212202 0.80 KMT2A (0.64) KDM4EALDH1A1KMT2APOLBMEN1
SCHEMBL13212207 0.80 KDM4E (0.61) KDM4EALDH1A1KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190176459-A1 POSITIVE TYPE PLANOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed
US-9738064-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2017-08-22 US disclosed
US-9029066-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2015-05-12 US disclosed
US-8993216-B2 Method of producing a planographic printing plate FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
EP-2106907-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-10-16 EP disclosed
US-20130260317-A1 METHOD OF PRODUCING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2013-10-03 US disclosed
EP-2489512-B1 A lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2013-08-28 EP disclosed
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 US disclosed
US-8304166-B2 Heat sensitive positive-working lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-11-06 US disclosed
US-20120266768-A1 Lithographic Printing Plate Precursor AGFA GRAPHICS NV (BE) 2012-10-25 US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 US disclosed
US-20100055610-A1 HEAT SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-03-04 US disclosed
EP-2159049-A1 A heat-sensitive positive-working lithographic printing plate precursor Agfa Graphics N.V. (BE) 2010-03-03 EP disclosed
US-20090253071-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-08 US disclosed
US-20090253071-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-08 US disclosed
EP-2106907-A2 Planographic printing plate precursor FUJIFILM Corporation (JP) 2009-10-07 EP disclosed
US-20090170028-A1 HEAT-SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-07-02 US disclosed
US-20090170028-A1 HEAT-SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-07-02 US disclosed
WO-2007099047-A1 A HEAT-SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2007-09-07 WO disclosed
EP-1826001-A1 A heat-sensitive positive-working lithographic printing plate precursor Agfa Graphics N.V. (BE) 2007-08-29 EP disclosed