SCHEMBL3820009

SCHEMBL3820009

C=CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 4/20 0.67
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
ALDH1A1 P00352 4/20 0.62
PKM P14618 2/20 0.62
GAA P10253 1/20 0.61
GFER P55789 1/20 0.61
POLB P06746 1/20 0.57
GRM4 Q14833 1/20 0.57
IL1RN P18510 1/20 0.56
KEAP1 Q14145 1/20 0.56
ERAP1 Q9NZ08 1/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568604 0.95 TGM2 (0.64) TGM2MEN1KMT2AALDH1A1PKM
SCHEMBL3821674 0.87 ALDH1A1 (0.71) TGM2MEN1KMT2AALDH1A1POLB
SCHEMBL14394819 0.87 CES1 (0.65) TGM2MEN1KMT2AALDH1A1POLB
SCHEMBL9568792 0.87 ALDH1A1 (0.71) TGM2MEN1KMT2AALDH1A1POLB
SCHEMBL9568677 0.85 TGM2 (0.58) TGM2MEN1KMT2AALDH1A1PKM
SCHEMBL9568796 0.85 TGM2 (0.58) TGM2MEN1KMT2AALDH1A1PKM
SCHEMBL9568497 0.85 LMNA (0.62) TGM2MEN1KMT2AALDH1A1PKM
SCHEMBL9568645 0.85 HDAC1 (0.62) TGM2MEN1KMT2AALDH1A1PKM
SCHEMBL14394824 0.84 ALDH1A1 (0.65) TGM2MEN1KMT2AALDH1A1GAA
SCHEMBL10031600 0.84 MEN1 (0.59) TGM2MEN1KMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192918-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-06-05 US disclosed
US-8192918-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-06-05 US disclosed
US-20100112476-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-05-06 US disclosed
US-20100112476-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-05-06 US disclosed
EP-1048981-B1 Methode for negative type image recording FUJIFILM CORP (JP) 2009-08-19 EP disclosed
EP-1219464-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-02-13 EP disclosed
US-6890700-B2 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
EP-1078736-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-01-28 EP disclosed
EP-0854388-B1 Negative-type image recording materials FUJI PHOTO FILM CO LTD (JP) 2003-08-13 EP disclosed
US-20020182538-A1 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJIFILM CORPORATION (JP) 2002-12-05 US disclosed
EP-1219464-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-07-03 EP disclosed
US-6238839-B1 DIMENSIONALLY STABLE METAL SUPPORT COATED WITH A HEAT-INSULATING LAYER, A HYDROPHILIC LAYER AND A THERMOSENSITIVE LIPOPHILIC LAYER; IMAGE QUALITY, MULTICOLOR PRINTS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 US disclosed
EP-1078736-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-02-28 EP disclosed
EP-1048981-A1 Negative type image recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
US-6068963-A CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
EP-0823659-B1 Negative type image recording material FUJI PHOTO FILM CO LTD (JP) 1999-12-01 EP disclosed
US-5948590-A CAPABLE OF PROCESSING DIRECTLY FROM COMPUTER AND OTHER DIGITAL DATA, WITH EXCELLENT PRINTING DURABILITY AT THE TIME OF PRINTING AND LACK OF STAINING. POLYMER, CURING AGENT, COMPOUND WHICH GENERATES AN ACID IN PRESENCE OF HEAT OR LIGHT. FUJI PHOTO FILM CO., LTD. (JP) 1999-09-07 US disclosed
EP-0854388-A2 Negative-type image recording materials FUJI PHOTO FILM CO., LTD. (JP) 1998-07-22 EP disclosed
EP-0823659-A1 Negative type image recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-02-11 EP disclosed
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed