Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067076 | 0.85 | VCAM1 (0.53) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL6912644 | 0.82 | VCAM1 (0.58) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL12065563 | 0.82 | POLB (0.44) | LMNAPOLBTNNI3KBRAFCA1 | |
| SCHEMBL2278928 | 0.81 | VCAM1 (0.53) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL12067917 | 0.80 | VCAM1 (0.56) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL12067872 | 0.79 | VCAM1 (0.57) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL15646981 | 0.78 | IDH2 (0.52) | VCAM1ALDH3A1ALDH1A1PTPN1HTT | |
| SCHEMBL30871305 | 0.76 | ALDH1A1 (0.67) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL6117960 | 0.76 | ALDH1A1 (0.67) | VCAM1ALDH3A1LMNAMAPTALDH1A1 | |
| SCHEMBL12065809 | 0.70 | VCAM1 (0.47) | VCAM1ALDH3A1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |