Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997273 | 0.90 | ALDH1A1 (0.37) | KIF11RPS6KB1AKT1HCRTR2GRIN2B | |
| SCHEMBL1000821 | 0.87 | KIF11 (0.41) | KIF11RPS6KB1RXFP1MAPTTDP1 | |
| SCHEMBL999019 | 0.85 | KIF11 (0.38) | KIF11RPS6KB1RXFP1AKT1ALDH1A1 | |
| SCHEMBL999201 | 0.84 | KIF11 (0.40) | KIF11RXFP1MAPTHCRTR2TP53 | |
| SCHEMBL998327 | 0.82 | KIF11 (0.42) | KIF11RXFP1MAPTTDP1MEN1 | |
| SCHEMBL998115 | 0.82 | KIF11 (0.52) | KIF11MAPTTDP1MEN1KMT2A | |
| SCHEMBL999416 | 0.81 | KIF11 (0.52) | KIF11MAPTKDM4ELMNATP53 | |
| SCHEMBL2033145 | 0.81 | KIF11 (0.43) | KIF11RXFP1TDP1ALDH1A1HPGD | |
| SCHEMBL2035529 | 0.81 | KIF11 (0.47) | KIF11MAPTRIPK1TP53 | |
| SCHEMBL2032812 | 0.80 | KIF11 (0.42) | KIF11RXFP1HCRTR2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872133-B2 | Tricyclic heterocycle compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-18 | — | — | US | disclosed |