SCHEMBL9979015

SCHEMBL9979015

CC(C)c1ccc(NC(=O)CC(CC(=O)Nc2ccc(C(C)C)cc2)C(=O)Nc2ccc(C(C)C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.59
HPGD P15428 3/20 0.59
FNTA P49354 1/20 0.54
FNTB P49356 1/20 0.54
RAB9A P51151 6/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
PTPN1 P18031 1/20 0.53
NPC1 O15118 3/20 0.52
KIF11 P52732 1/20 0.50
LMNA P02545 3/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979420 0.87 SMN1; SMN2 (0.59) SMN1; SMN2HPGDFNTAFNTBRAB9A
SCHEMBL12018050 0.84 PTPN1 (0.73) SMN1; SMN2HPGDFNTAFNTBRAB9A
SCHEMBL9979332 0.83 POLB (0.63) SMN1; SMN2FNTAFNTBPTPN1MEN1
SCHEMBL12545584 0.82 SMN1; SMN2 (0.67) SMN1; SMN2HPGDRAB9ACRHBPCRHR2
SCHEMBL9979079 0.81 HPGD (0.52) SMN1; SMN2HPGDFNTAFNTBRAB9A
SCHEMBL31136175 0.81 SMN1; SMN2 (0.61) SMN1; SMN2HPGDFNTAFNTBRAB9A
SCHEMBL9979328 0.80 HDAC3 (0.54) SMN1; SMN2HPGDRAB9ACRHBPCRHR2
SCHEMBL9978869 0.79 GAA (0.56) SMN1; SMN2FNTAFNTBCRHBPCRHR2
SCHEMBL104611 0.79 SMN1; SMN2 (0.67) SMN1; SMN2HPGDRAB9ACRHBPCRHR2
SCHEMBL9979295 0.79 ALDH1A1 (0.62) SMN1; SMN2FNTAFNTBRAB9ACRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed