SCHEMBL9979079

SCHEMBL9979079

CC(C)c1cccc(NC(=O)CC(CC(=O)Nc2cccc(C(C)C)c2)C(=O)Nc2cccc(C(C)C)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.52
ALDH1A1 P00352 1/20 0.52
FADS1 O60427 1/20 0.50
KDM4E B2RXH2 1/20 0.50
NLRP3 Q96P20 1/20 0.49
CA2 P00918 1/20 0.48
GAA P10253 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
LMNA P02545 3/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
SIGMAR1 Q99720 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979343 0.88 HPGD (0.56) HPGDALDH1A1FADS1KDM4ENLRP3
SCHEMBL11795655 0.86 SMN1; SMN2 (0.63) HPGDALDH1A1FADS1KDM4ENLRP3
SCHEMBL12569855 0.84 FADS1 (0.55) HPGDALDH1A1FADS1KDM4ENLRP3
SCHEMBL9979425 0.82 HPGD (0.59) HPGDALDH1A1KDM4ERAB9AMEN1
SCHEMBL9979015 0.81 SMN1; SMN2 (0.59) HPGDALDH1A1RAB9ASMN1; SMN2MEN1
SCHEMBL6409278 0.81 POLB (0.63) ALDH1A1FADS1KDM4ENLRP3CA2
SCHEMBL5950517 0.81 SMN1; SMN2 (0.61) ALDH1A1FADS1CA2RAB9ASMN1; SMN2
SCHEMBL4002308 0.80 SMN1; SMN2 (0.55) HPGDALDH1A1FADS1KDM4ENLRP3
SCHEMBL13547747 0.80 FADS1 (0.54) HPGDALDH1A1FADS1KDM4ENLRP3
SCHEMBL967250 0.80 FADS1 (0.57) HPGDALDH1A1FADS1KDM4ENLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed