SCHEMBL9979295

SCHEMBL9979295

COc1ccc(NC(=O)CC(CC(=O)Nc2ccc(OC)cc2)C(=O)Nc2ccc(OC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
HTT P42858 3/20 0.62
L3MBTL1 Q9Y468 1/20 0.61
KMT2A Q03164 3/20 0.60
LMNA P02545 2/20 0.59
GAA P10253 1/20 0.59
FNTA P49354 1/20 0.58
FNTB P49356 1/20 0.58
MTNR1B P49286 1/20 0.57
POLB P06746 1/20 0.56
RAB9A P51151 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPC1 O15118 1/20 0.56
MEN1 O00255 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CRHBP P24387 1/20 0.56
CYP2C19 P33261 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978775 0.87 HTT (0.63) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL9978996 0.84 POLB (0.69) ALDH1A1HTTKMT2ALMNAGAA
SCHEMBL6511328 0.83 MTNR1B (0.72) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL19592288 0.83 KMT2A (0.71) ALDH1A1HTTL3MBTL1KMT2APOLB
SCHEMBL9979332 0.81 POLB (0.63) ALDH1A1KMT2AFNTAFNTBPOLB
SCHEMBL2089593 0.81 L3MBTL1 (0.71) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL9313874 0.81 L3MBTL1 (0.76) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL10954626 0.81 LMNA (0.86) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL31136179 0.81 L3MBTL1 (0.61) ALDH1A1HTTL3MBTL1KMT2ALMNA
SCHEMBL28984812 0.81 ATM (0.61) ALDH1A1HTTL3MBTL1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed