SCHEMBL9979425

SCHEMBL9979425

Cc1cccc(NC(=O)CC(CC(=O)Nc2cccc(C)c2)C(=O)Nc2cccc(C)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HDAC3 O15379 2/20 0.56
HDAC1 Q13547 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC10 Q969S8 2/20 0.56
HDAC11 Q96DB2 2/20 0.56
HDAC8 Q9BY41 2/20 0.56
HDAC6 Q9UBN7 2/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
HSD17B10 Q99714 1/20 0.56
NCOR2 Q9Y618 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979197 0.88 HPGD (0.59) HPGDMEN1KMT2AHDAC3HDAC1
SCHEMBL9979140 0.83 HTT (0.69) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL9979313 0.82 MAPT (0.59) HPGDMEN1KMT2AHDAC3HDAC1
SCHEMBL9979079 0.82 HPGD (0.52) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL29575656 0.82 HPGD (0.68) HPGDMEN1KMT2AHDAC3HDAC1
SCHEMBL12327192 0.82 HPGD (0.68) HPGDMEN1KMT2AHDAC3HDAC1
SCHEMBL2014002 0.81 MEN1 (0.72) HPGDMEN1KMT2AHDAC3HDAC1
SCHEMBL9978520 0.81 KCNJ6 (0.55) HPGDMEN1KMT2AHDAC3HDAC8
SCHEMBL9979332 0.80 POLB (0.63) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL9979214 0.80 NLRP3 (0.51) HPGDHDAC3HDAC1HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2726940-B1 YELLOW TONER CANON KK (JP) 2017-01-18 EP disclosed
US-9102811-B2 Pigment dispersion, ink composition including pigment dispersion, and color filter yellow resist composition including pigment dispersion CANON KABUSHIKI KAISHA (JP) 2015-08-11 US disclosed
US-9012115-B2 Yellow toner CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-20140080049-A1 YELLOW TONER CANON KABUSHIKI KAISHA (JP) 2014-03-20 US disclosed
US-20140080063-A1 PIGMENT DISPERSION, INK COMPOSITION INCLUDING PIGMENT DISPERSION, AND COLOR FILTER YELLOW RESIST COMPOSITION INCLUDING PIGMENT DISPERSION CANON KABUSHIKI KAISHA (JP) 2014-03-20 US disclosed
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
WO-2013002294-A1 YELLOW TONER CANON KABUSHIKI KAISHA (JP) 2013-01-03 WO disclosed
WO-2012153669-A1 PIGMENT DISPERSION, INK COMPOSITION INCLUDING PIGMENT DISPERSION, AND COLOR FILTER YELLOW RESIST COMPOSITION INCLUDING PIGMENT DISPERSION CANON KABUSHIKI KAISHA (JP) 2012-11-15 WO disclosed
US-20120251939-A1 PIGMENT DISPERSION AND YELLOW TONER CANON KABUSHIKI KAISHA (JP) 2012-10-04 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed