SCHEMBL9979197

SCHEMBL9979197

Cc1cccc(NC(=O)CC(C(=O)Nc2cccc(C)c2)C(CC(=O)Nc2cccc(C)c2)C(=O)Nc2cccc(C)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
MAPK1 P28482 1/20 0.57
HDAC3 O15379 2/20 0.56
HDAC1 Q13547 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC10 Q969S8 2/20 0.56
HDAC11 Q96DB2 2/20 0.56
HDAC8 Q9BY41 2/20 0.56
HDAC6 Q9UBN7 2/20 0.56
ALDH1A1 P00352 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
NPC1 O15118 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979425 0.88 HPGD (0.59) HPGDMEN1KMT2AMAPK1HDAC3
SCHEMBL9979154 0.83 HTT (0.59) MEN1KMT2AHDAC3HDAC1HDAC2
SCHEMBL9979343 0.82 HPGD (0.56) HPGDMEN1KMT2AALDH1A1RAB9A
SCHEMBL9979430 0.82 MAPT (0.59) HPGDMEN1KMT2AMAPK1HDAC3
SCHEMBL29575656 0.82 HPGD (0.68) HPGDMEN1KMT2AMAPK1HDAC3
SCHEMBL12327192 0.82 HPGD (0.68) HPGDMEN1KMT2AMAPK1HDAC3
SCHEMBL2014002 0.81 MEN1 (0.72) HPGDMEN1KMT2AMAPK1HDAC3
SCHEMBL6062563 0.81 LMNA (0.59) HPGDMEN1KMT2AALDH1A1POLB
SCHEMBL9979086 0.81 KCNJ6 (0.59) HPGDMEN1KMT2AHDAC3HDAC8
SCHEMBL9979382 0.80 POLB (0.63) HPGDHDAC3HDAC1HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed