SCHEMBL9979382

SCHEMBL9979382

Cc1ccc(NC(=O)CC(C(=O)Nc2ccc(C)cc2)C(CC(=O)Nc2ccc(C)cc2)C(=O)Nc2ccc(C)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.63
SMN1; SMN2 Q16637 2/20 0.60
MAPT P10636 2/20 0.56
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
HDAC3 O15379 2/20 0.51
HDAC1 Q13547 2/20 0.51
HDAC2 Q92769 2/20 0.51
HDAC10 Q969S8 2/20 0.51
HDAC11 Q96DB2 2/20 0.51
HDAC8 Q9BY41 2/20 0.51
HDAC6 Q9UBN7 2/20 0.51
PTPN1 P18031 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51
NCOR2 Q9Y618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9979332 0.86 POLB (0.63) POLBSMN1; SMN2MAPTALDH1A1TDP1
SCHEMBL6062563 0.83 LMNA (0.59) POLBSMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL9979420 0.83 SMN1; SMN2 (0.59) POLBSMN1; SMN2MAPTALDH1A1PTPN1
SCHEMBL9979379 0.83 CRHBP (0.57) SMN1; SMN2ALDH1A1HDAC3HDAC1HDAC2
SCHEMBL9979154 0.82 HTT (0.59) MAPTTDP1HDAC3HDAC1HDAC2
SCHEMBL9979131 0.82 GAA (0.56) POLBSMN1; SMN2MAPTALDH1A1HDAC3
SCHEMBL8361578 0.81 PTPN1 (0.76) POLBSMN1; SMN2MAPTALDH1A1TDP1
SCHEMBL9979253 0.81 POLB (0.67) POLBMAPTALDH1A1HDAC3HDAC1
SCHEMBL9979291 0.81 NPC1 (0.49) POLBSMN1; SMN2MAPTHDAC3HDAC11
SCHEMBL9978775 0.81 HTT (0.63) SMN1; SMN2MAPTALDH1A1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed