Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979407 | 0.87 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL13167575 | 0.83 | PTPN1 (0.69) | NPC1RAB9ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL9979086 | 0.82 | KCNJ6 (0.59) | RAB9ASMN1; SMN2MEN1MAPTXBP1 | |
| SCHEMBL9979382 | 0.81 | POLB (0.63) | SMN1; SMN2MAPTHDAC3HDAC11HDAC8 | |
| SCHEMBL13778192 | 0.79 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2MAPK1MEN1 | |
| SCHEMBL6062563 | 0.79 | LMNA (0.59) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL9979379 | 0.79 | CRHBP (0.57) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9979420 | 0.79 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL9979131 | 0.78 | GAA (0.56) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL12233865 | 0.78 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492468-B2 | Polypropylene resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20110301268-A1 | POLYPROPYLENE RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |