SCHEMBL9979393

SCHEMBL9979393

Cc1cc(F)ccc1NC(=O)c1cc(C(=O)Nc2ccc(F)cc2C)cc(C(=O)Nc2ccc(F)cc2C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.55
CYP2C19 P33261 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
GFER P55789 1/20 0.55
HDAC1 Q13547 3/20 0.54
MAPT P10636 4/20 0.53
ALDH1A1 P00352 4/20 0.53
LMNA P02545 2/20 0.53
CYP2C9 P11712 1/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
GAA P10253 1/20 0.51
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
KCNMA1 Q12791 1/20 0.50
TAS1R3 Q7RTX0 2/20 0.49
TAS1R1 Q7RTX1 2/20 0.49
TAS1R2 Q8TE23 2/20 0.49
CYP3A4 P08684 1/20 0.49
HDAC3 O15379 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6479806 0.88 HDAC1 (0.68) CYP1A2CYP2C19SMN1; SMN2GFERHDAC1
SCHEMBL19462130 0.83 HDAC1 (0.73) SMN1; SMN2HDAC1MAPTALDH1A1LMNA
SCHEMBL18147630 0.82 MAPT (0.63) CYP1A2CYP2C19SMN1; SMN2GFERHDAC1
SCHEMBL1029643 0.81 ALDH1A1 (0.55) SMN1; SMN2HDAC1MAPTALDH1A1LMNA
SCHEMBL4449040 0.81 TAS1R3 (0.69) CYP1A2CYP2C19SMN1; SMN2GFERMAPT
SCHEMBL15296458 0.80 ALDH1A1 (0.52) CYP1A2CYP2C19SMN1; SMN2GFERMAPT
SCHEMBL28265144 0.80 ALDH1A1 (0.52) CYP1A2CYP2C19SMN1; SMN2HDAC1MAPT
SCHEMBL12190867 0.79 SCN10A (0.67) CYP2C19SMN1; SMN2GFERHDAC1LMNA
SCHEMBL11406833 0.79 ALDH1A1 (0.54) SMN1; SMN2MAPTALDH1A1LMNARAB9A
SCHEMBL15708434 0.79 ALDH1A1 (0.61) CYP2C19SMN1; SMN2MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492468-B2 Polypropylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-23 US disclosed
US-20110301268-A1 POLYPROPYLENE RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-08 US disclosed