Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | FTH1 | P02794 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409470 | 1.00 | FNTA (0.33) | FNTAFNTBPGGT1BPTGS2KDR | |
| SCHEMBL13216859 | 0.90 | FNTA (0.32) | FNTAFNTBPGGT1BPTGS2 | |
| SCHEMBL14486589 | 0.82 | CYP3A4 (0.35) | CYP3A4FTH1CYP2C9CYP2C19 | |
| SCHEMBL9979496 | 0.78 | HSD11B1 (0.33) | HSD11B1CYP3A4HSD11B2 | |
| SCHEMBL9979494 | 0.78 | HSD11B1 (0.35) | KDRHSD11B1CYP3A4HSD11B2 | |
| SCHEMBL9979495 | 0.75 | CYP3A4 (0.36) | CYP3A4FTH1CYP2C9CYP2C19 | |
| SCHEMBL31424073 | 0.69 | FNTA (0.58) | FNTAFNTBPGGT1BPTGS2CYP3A4 | |
| SCHEMBL31424068 | 0.69 | FNTA (0.58) | FNTAFNTBPGGT1BPTGS2CYP3A4 | |
| SCHEMBL16943993 | 0.64 | ALDH1A1 (0.39) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13355527 | 0.63 | CYP3A4 (0.39) | CYP3A4FTH1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124654-B2 | Derivatives of hypoestoxide and related compounds | IMMUNE MODULATION, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100120853-A1 | Derivatives of Hypoestoxide and Related Compounds | IMMUNE MODULATION, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-09 | — | — | US | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | FNTA 2727/4885FNTB 1297/4885PGGT1B 2575/4885 |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | FNTA 2727/4885FNTB 1297/4885PGGT1B 2575/4885 |
| US-20100120853-A1 | Derivatives of Hypoestoxide and Related Compounds | CYP8B1, HAAO, CYP27A1 | FNTA 84/4885FNTB 210/4885PGGT1B 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.