SCHEMBL9979548

SCHEMBL9979548

CO/N=C/c1ccc(-c2ccccc2NC(=O)c2cn(C)nc2C(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
LMNA P02545 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
IRAK4 Q9NWZ3 9/20 0.39
ATM Q13315 1/20 0.39
POLB P06746 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NTRK1 P04629 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
CHRM3 P20309 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23748525 1.00 ALDH1A1 (0.41) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL9979704 1.00 ALDH1A1 (0.41) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL343590 0.88 CHRM3 (0.39) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL343589 0.88 CHRM3 (0.39) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL4790543 0.88 IRAK4 (0.37) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL4790540 0.88 IRAK4 (0.37) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL13215928 0.87 CHRM3 (0.41) IRAK4CHRM3
SCHEMBL14781428 0.86 ATM (0.42) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL9979550 0.86 ATM (0.55) ALDH1A1LMNAKDM4EMAPTHTT
SCHEMBL14578389 0.85 LMNA (0.47) ALDH1A1LMNAKDM4EMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11578051-B2 Thiophene carboxamide derivative and plant disease control agent comprising same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-02-14 US disclosed
US-20210347755-A1 THIOPHENE CARBOXAMIDE DERIVATIVE AND PLANT DISEASE CONTROL AGENT COMPRISING SAME FARMHANNONG CO., LTD (KR) 2021-11-11 US disclosed
EP-3865479-A1 THIOPHENE CARBOXAMIDE DERIVATIVE AND PLANT DISEASE CONTROL AGENT COMPRISING SAME Korea Research Institute of Chemical Technology (KR) 2021-08-18 EP disclosed
EP-1305292-B1 BIPHENYL CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2012-06-20 EP disclosed
US-7176228-B2 Pyrazole biphenylcarboxamides BAYER CROPSCIENCE AG (DE) 2007-02-13 US disclosed
US-7176228-B2 Pyrazole biphenylcarboxamides BAYER CROPSCIENCE AG (DE) 2007-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210347755-A1 THIOPHENE CARBOXAMIDE DERIVATIVE AND PLANT DISEASE CONTROL AGENT COMPRISING SAME BROX, GTF3C4, GTF3C2 ALDH1A1 3886/4885LMNA 4707/4885KDM4E 46/4885
US-11578051-B2 Thiophene carboxamide derivative and plant disease control agent comprising same BROX, GTF3C4, GTF3C2 ALDH1A1 3886/4885LMNA 4707/4885KDM4E 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.