Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CBLB | Q13191 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979658 | 0.86 | UGCG (0.42) | GRM1UGCGMEN1KMT2ARAB9A | |
| SCHEMBL9979657 | 0.86 | NPC1 (0.55) | GRM1UGCGMEN1KMT2ARAB9A | |
| SCHEMBL9979600 | 0.86 | UGCG (0.42) | GRM1UGCGMEN1KMT2ARAB9A | |
| SCHEMBL9979557 | 0.83 | UGCG (0.45) | UGCGFPR1FPR2CBLB | |
| SCHEMBL9979552 | 0.80 | UGCG (0.41) | UGCGRAB9ANPC1PKMCBLB | |
| SCHEMBL9979649 | 0.78 | HSP90AA1 (0.47) | GRM1UGCGMEN1KMT2ARAB9A | |
| SCHEMBL9979630 | 0.74 | SLC6A4 (0.50) | GRM1UGCGRAB9ANPC1HTR2C | |
| SCHEMBL9979484 | 0.73 | UGCG (0.43) | GRM1UGCGMEN1KMT2ARAB9A | |
| SCHEMBL9979599 | 0.72 | NPC1 (0.55) | GRM1UGCGMEN1KMT2ARAB9A | |
| SCHEMBL10085860 | 0.72 | TP53 (0.61) | GRM1UGCGMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |