Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 6/20 | 0.45 |
| ▸ | CBLB | Q13191 | 8/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979554 | 0.87 | UGCG (0.43) | UGCGCBLBPTGS1PTGS2 | |
| SCHEMBL9979552 | 0.84 | UGCG (0.41) | UGCGCBLB | |
| SCHEMBL9979657 | 0.83 | NPC1 (0.55) | UGCGCBLB | |
| SCHEMBL9979556 | 0.83 | GRM1 (0.43) | UGCGCBLBFPR1FPR2 | |
| SCHEMBL9979658 | 0.83 | UGCG (0.42) | UGCGCBLB | |
| SCHEMBL9979551 | 0.83 | UGCG (0.45) | UGCGCBLBCHRNB2HTR1BSLC6A4 | |
| SCHEMBL9979553 | 0.80 | UGCG (0.43) | UGCGCBLBPTGS1PTGS2 | |
| SCHEMBL9979629 | 0.77 | PPARD (0.41) | UGCGCBLBFPR1FPR2CHRNB2 | |
| SCHEMBL9979627 | 0.76 | UGCG (0.45) | UGCGCBLBFPR2CHRNB2HTR1B | |
| SCHEMBL9979509 | 0.76 | UGCG (0.42) | UGCGCHRNB2HTR1BSLC6A4CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |