Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | UGCG | Q16739 | 4/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 4/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979518 | 0.87 | UGCG (0.38) | UGCGGRM1CHRNB2HTR1BSLC6A4 | |
| SCHEMBL9979580 | 0.85 | PKM (0.41) | UGCGGRM1 | |
| SCHEMBL9979506 | 0.83 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL9979709 | 0.81 | PPARD (0.50) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979608 | 0.80 | PPARD (0.50) | PPARDPPARAUGCGPPARG | |
| SCHEMBL9979551 | 0.78 | UGCG (0.45) | UGCGCHRNB2HTR1BSLC6A4CHRNA4 | |
| SCHEMBL9979557 | 0.77 | UGCG (0.45) | UGCGFPR1FPR2CHRNB2HTR1B | |
| SCHEMBL9979554 | 0.75 | UGCG (0.43) | UGCGCBLB | |
| SCHEMBL9979706 | 0.74 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL9979632 | 0.73 | PPARD (0.60) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |