Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876703 | 0.97 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL2068684 | 0.86 | PTGDR (0.43) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL5511641 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL24133236 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL24133244 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL9979636 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL2876705 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL15372541 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL2876699 | 0.75 | RXRA (0.54) | ALDH1A1KDM4EHSD17B10HPGDMEN1 | |
| SCHEMBL9979602 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |