Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979673 | 0.91 | RAB9A (0.36) | PPARDPPARAPPARGNPC1PKM | |
| SCHEMBL9979674 | 0.89 | PPARD (0.47) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL9979498 | 0.87 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL9979646 | 0.83 | CYP11B1 (0.40) | PPARDPPARAPPARG | |
| SCHEMBL9979609 | 0.81 | PPARA (0.41) | PPARDPPARAPPARG | |
| SCHEMBL9979575 | 0.80 | PPARA (0.42) | PPARDPPARAPPARGFFAR1NPC1 | |
| SCHEMBL9979488 | 0.79 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL9979490 | 0.79 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL9979566 | 0.78 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL9979604 | 0.78 | PPARD (0.62) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |