Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979646 | 0.90 | CYP11B1 (0.40) | PPARDPPARANR1H3PPARGUGCG | |
| SCHEMBL9979498 | 0.90 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL9979579 | 0.89 | PPARD (0.41) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL9979605 | 0.81 | PPARD (0.47) | PPARDPPARAFFAR1PPARGUGCG | |
| SCHEMBL9979609 | 0.81 | PPARA (0.41) | PPARDPPARAPPARG | |
| SCHEMBL9979673 | 0.81 | RAB9A (0.36) | PPARDPPARANR1H3PPARGUGCG | |
| SCHEMBL9979641 | 0.80 | PPARD (0.59) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL9979564 | 0.80 | PPARD (0.59) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL9979477 | 0.79 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL9979489 | 0.79 | PPARD (0.67) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |