Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | UGCG | Q16739 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979673 | 0.92 | RAB9A (0.36) | CYP11B1CYP11B2PPARAPPARDUGCG | |
| SCHEMBL9979609 | 0.91 | PPARA (0.41) | CYP11B1CYP11B2PPARAPPARDPPARG | |
| SCHEMBL9979674 | 0.90 | PPARD (0.47) | PPARAPPARDUGCGPPARGNR1H3 | |
| SCHEMBL9979691 | 0.84 | CYP11B1 (0.40) | CYP11B1CYP11B2PPARAPPARDUGCG | |
| SCHEMBL9979485 | 0.83 | PPARD (0.47) | CYP11B1CYP11B2PPARAPPARDUGCG | |
| SCHEMBL9979638 | 0.83 | PPARD (0.47) | CYP11B1CYP11B2PPARAPPARDUGCG | |
| SCHEMBL9979579 | 0.83 | PPARD (0.41) | PPARAPPARDPPARG | |
| SCHEMBL9979593 | 0.82 | PPARD (0.50) | CYP11B1CYP11B2PPARAPPARDUGCG | |
| SCHEMBL9979498 | 0.82 | PPARD (0.51) | PPARAPPARDPPARG | |
| SCHEMBL9979475 | 0.82 | PPARD (0.53) | PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |