Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.48 |
| ▸ | BCL2 | P10415 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464391 | 0.91 | PPARG (0.50) | MCL1PPARGPPARDPPARAPLA2G4A | |
| SCHEMBL29138523 | 0.85 | MTNR1A (0.56) | MAPTKMT2A | |
| SCHEMBL4478676 | 0.81 | PPARD (0.56) | MCL1PPARGPPARDPPARABCL2 | |
| SCHEMBL30395677 | 0.81 | PPARD (0.56) | MCL1PPARGPPARDPPARABCL2 | |
| SCHEMBL4467932 | 0.81 | PPARG (0.45) | MCL1PPARGPPARDPPARAPLA2G4A | |
| SCHEMBL4468257 | 0.80 | CA12 (0.48) | MCL1PPARGPPARDPPARAPLA2G4A | |
| SCHEMBL20037218 | 0.80 | TDP1 (0.53) | MAPTKMT2A | |
| SCHEMBL2006435 | 0.80 | MCL1 (0.45) | MCL1PPARGPPARDPPARAPLA2G4A | |
| SCHEMBL2156900 | 0.79 | PLA2G2A (0.56) | MCL1PPARGPPARDPPARABCL2 | |
| SCHEMBL2006433 | 0.78 | MCL1 (0.43) | MCL1PPARGPPARDPPARAPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |