Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200019 | 0.87 | MTNR1A (0.60) | MTNR1AMTNR1BALDH1A1MAPTHSD17B10 | |
| SCHEMBL4464391 | 0.85 | PPARG (0.50) | MAPTKMT2A | |
| SCHEMBL9979614 | 0.85 | MCL1 (0.51) | MAPTKMT2A | |
| SCHEMBL30396580 | 0.84 | F2 (0.45) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL3689068 | 0.84 | F2 (0.45) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL16536196 | 0.84 | PDE4B (0.55) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL20037218 | 0.83 | TDP1 (0.53) | ALDH1A1MAPTMEN1KMT2AHTR2C | |
| SCHEMBL1666483 | 0.83 | NTSR1 (0.52) | ALDH1A1MAPTPDE4BPDE4DATM | |
| SCHEMBL20037274 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTR2CATMTNFKDM4E | |
| SCHEMBL4483940 | 0.83 | ATM (0.43) | MTNR1AMTNR1BALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069720-A | 5-HT 2A Receptor agonist, preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |