Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 6/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | UGCG | Q16739 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979700 | 0.90 | PPARD (0.46) | PPARDPPARAPPARGSLC26A3PTGER4 | |
| SCHEMBL9979623 | 0.85 | PPARD (0.67) | PPARDPPARAPPARGFFAR1PTGER4 | |
| SCHEMBL9979617 | 0.81 | PPARD (0.46) | PPARDPPARAPPARGPTGER4UGCG | |
| SCHEMBL9979633 | 0.77 | PPARD (0.55) | PPARDPPARAPPARGFFAR1PTGER4 | |
| SCHEMBL9979510 | 0.76 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL9979640 | 0.74 | PPARD (0.51) | PPARDPPARAPPARGFFAR1PTGER4 | |
| SCHEMBL9979669 | 0.74 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5639006 | 0.73 | PPARD (0.89) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL9979624 | 0.73 | PPARD (0.38) | PPARDPPARAPPARGUGCG | |
| SCHEMBL5640961 | 0.73 | PPARD (0.82) | PPARDPPARAPPARGFFAR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |