Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9979668 | 0.92 | POLB (0.43) | MAPTTP53SMN1; SMN2POLBTSHR | |
| SCHEMBL9979703 | 0.91 | L3MBTL1 (0.36) | PPARDPPARAPPARGMAPTSMN1; SMN2 | |
| SCHEMBL9979617 | 0.90 | PPARD (0.46) | PPARDPPARAPPARGMAPTTP53 | |
| SCHEMBL9979510 | 0.84 | PPARD (0.53) | PPARDPPARAPPARGMAPTTP53 | |
| SCHEMBL9979700 | 0.84 | PPARD (0.46) | PPARDPPARAPPARGMAPTTP53 | |
| SCHEMBL9979625 | 0.83 | MAPT (0.47) | MAPTTP53SMN1; SMN2POLBTSHR | |
| SCHEMBL9979660 | 0.82 | PPARD (0.41) | PPARDPPARAPPARGMAPTSMN1; SMN2 | |
| SCHEMBL9979646 | 0.78 | CYP11B1 (0.40) | PPARDPPARAPPARGUGCGNR1H3 | |
| SCHEMBL9979618 | 0.77 | PPARD (0.44) | PPARDPPARAPPARGMAPTPOLB | |
| SCHEMBL9979584 | 0.75 | POLB (0.44) | PPARDMAPTPOLBTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012081570-A1 | LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR | あすか製薬株式会社 (JP) | 2012-06-21 | — | — | WO | disclosed |