SCHEMBL9979633 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	PPARD	Q03181	7/20	0.55

▸	PPARA	Q07869	6/20	0.51

▸	PPARG	P37231	1/20	0.51

▸	FFAR1	O14842	2/20	0.45

▸	FFAR4	Q5NUL3	1/20	0.37

▸	MAPT	P10636	1/20	0.36

▸	ALOX15	P16050	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	PTGER4	P35408	1/20	0.36

▸	ROCK2	O75116	1/20	0.35

▸	ROCK1	Q13464	1/20	0.35

▸	MAOB	P27338	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9979623	0.92	PPARD (0.67)	PPARDPPARAPPARGFFAR1PTGER4
SCHEMBL9979618	0.90	PPARD (0.44)	PPARDPPARAPPARGFFAR1MAPT
SCHEMBL9979640	0.90	PPARD (0.51)	PPARDPPARAPPARGFFAR1MAPT
SCHEMBL9979669	0.90	PPARD (0.53)	PPARDPPARAPPARGFFAR1MAPT
SCHEMBL9979660	0.84	PPARD (0.41)	PPARDPPARAPPARGFFAR1MAPT
SCHEMBL9979532	0.84	PPARD (0.55)	PPARDPPARAPPARGFFAR1FFAR4
SCHEMBL9979510	0.82	PPARD (0.53)	PPARDPPARAPPARGFFAR1MAPT
SCHEMBL9979584	0.81	POLB (0.44)	PPARDFFAR1MAPTMAOB
SCHEMBL9979520	0.80	PPARD (0.43)	PPARDPPARAPPARGFFAR1MAPT
SCHEMBL9979524	0.77	FFAR1 (0.49)	PPARDPPARAPPARGFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012081570-A1	LACTAM COMPOUND OR A SALT THEREOF, AND PPAR ACTIVATOR	あすか製薬株式会社 (JP)	2012-06-21	—	—	WO	disclosed