Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15581106 | 0.85 | KDM4E (0.46) | EGFRPDGFRBPDGFRATERTMAPT | |
| SCHEMBL9979780 | 0.83 | MAPT (0.46) | EGFRPDGFRBPDGFRAMAPTSNCA | |
| SCHEMBL9979789 | 0.82 | EGFR (0.36) | EGFRPDGFRBPDGFRAMAPTSNCA | |
| SCHEMBL9979783 | 0.78 | EGFR (0.33) | EGFRPDGFRBPDGFRAMAPTALDH1A1 | |
| SCHEMBL9979788 | 0.78 | EGFR (0.34) | EGFRPDGFRBPDGFRAMAPTSNCA | |
| SCHEMBL9979787 | 0.77 | KDM4E (0.32) | EGFRPDGFRBPDGFRATERTALDH1A1 | |
| SCHEMBL31255815 | 0.75 | LCK (0.42) | MAPTACHEKMT2AMEN1LMNA | |
| SCHEMBL5358508 | 0.75 | LCK (0.42) | MAPTACHEKMT2AMEN1LMNA | |
| SCHEMBL8320612 | 0.75 | EGFR (0.36) | EGFRPDGFRBPDGFRAMAPTSNCA | |
| SCHEMBL107294 | 0.75 | PTPN22 (0.38) | EGFRPDGFRBPDGFRAMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9978474-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | UNITED STATES DEPARTMENT OF ENERGY | 2016-08-25 | — | — | US | disclosed |
| US-9269473-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-23 | — | — | US | disclosed |
| WO-2012082213-A2 | CONDUCTIVE OPEN FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | GJB2, OR10J3, EPCAM | EGFR 3295/4885PDGFRB 3652/4885PDGFRA 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.